The pathogenesis of diabetic foot ulcer

Serious lower extremity complications from diabetes include foot ulcers, infections, peripheral vascular disease, lower extremity amputations, and Charcot osteoarthropathy of the foot. 15% of people with diabetes will develop foot ulcers in their lifetime. The causes of diabetic foot ulcers are often multifaceted, among which diabetic neuropathy, ischemic lesions or neuro-ischemic lesions are the most important factors causing ulceration.

The mechanism of foot ulcers in diabetic patients is very complex. It is the result of the combined action of many intrinsic and extrinsic factors. Intrinsic risk factors include: nerve and vascular disease, immune factors (susceptibility to infection), foot deformity, joint activity Restriction, kidney disease, age, duration of diabetes, visual impairment, and history of ulcers; external factors include: increased plantar pressure, biomechanical microtrauma caused by shoe compression, navel suit, temperature-induced injury, podiatrist mishandling, occupational injury, chemical burns, living alone, smoking, lack of knowledge about diabetes, psychological problems, etc. The complexity of pathogenesis determines the specificity of clinical manifestations. The healing process of foot ulcers is different from that of general ulcers, and is also affected by the cross-influence of many of the above-mentioned internal and external factors, so the treatment and treatment will be very difficult. A correct understanding of the role of various factors in the occurrence of diabetic foot ulcers is of great significance for guiding ulcer treatment, promoting wound healing and preventing the occurrence of foot ulcers.

At present, the generally accepted view on the pathogenesis of diabetic foot ulcer is the ternary theory of diabetic foot: namely, the three most important risk factors of diabetic neuropathy, diabetic ischemic lesions and local infection are the basis, and the external minor trauma is the basis. Triggers can promote the formation and progression of ulcers.

Emphasize the four irreplaceable important alginate dressing links in wound management: local decompression; thorough debridement; control of infection; improvement of ischemia.

It should be remembered that when treating ulcers, it is important to choose those drugs that have been proven to be effective in randomized controlled studies. In 1934, the famous diabetes scholar Elliott P.joslin said: "We should firmly believe that ulcer necrosis in diabetes is not caused by birth, but caused by human factors."

How to treat allergic dermatitis, allergic rhinitis, hormone face? Allergic dermatitis is a skin disease caused by allergens. Allergic rhinitis is referred to as allergic rhinitis, also known as aller

How to treat allergic dermatitis, allergic rhinitis, hormone face?
Allergic dermatitis is a skin disease caused by allergens. Allergic rhinitis is referred to as allergic rhinitis, also known as allergic rhinitis. Hormone face is a kind of drug-induced acne, also known as hormonal acne, which is a serious skin disease caused by the toxic and side effects of hormones caused by intermittent or prolonged abuse of hormone ointments or cosmetic cosmetics containing hormones.
Fuminan Medical Care Spray can physically block and repair skin redness, swelling and damage caused by exogenous allergies. It forms a protective layer on the wound surface, and acts as a nursing and physical barrier for the skin and superficial wounds.


How to use Fuminan wound dressing?
The method of use is direct spraying.
Allergic rhinitis: raise the head at a 45-degree angle, spray 10 sprays directly into each nasal cavity, stay for 5 minutes and discharge, 6 times a day, seven days as a course of treatment.
Allergic dermatitis: spray this product for 5 minutes in the area of ​​inflammation and the surrounding 2cm, 6 times a day, 7 days as a course of treatment.
Hormone face: spray this product in the area of ​​inflammation and the surrounding area of ​​2cm for 5 minutes, 8 times a day, until the skin color returns to normal.

These directories are usually designed in alphabetical order and are colostomy bag easily accessible

colostomy bag

These directories are usually designed in alphabetical order and are colostomy bag easily accessible. Just do a search on the product you are looking for. A B2B portal has become an indispensable device for growing all types of businesses. These traders become a b2b exporter for the supply of goods internationally.


A B2B portal is a set of web pages in which both sellers and large-scale buyers can register to start business.B2B manufacturers are the people who are engaged in producing goods and services for other businesses. You can find a list of all exporters or suppliers of B2B in any of the online B2B directory.

All at once, it also acts as mediator for all buyers, distributors and wholesalers source of their choice without facing any difficulty or problem. Basically, they are the manufacturers and suppliers who are already running the business units. It acts as a base where vendors can display the company information along with the features and prices of the products and the minimum amount approved to attract big-scale suppliers, wholesalers, buyers or distributors worldwide.

All you need is to sign a B2B portal and register your business on it. A B2B portal also provides useful and important articles related to business leads to help you reach new heights of growth

Any type of supplier or manufacturer of different commodities which are recorded in a B2B portal for easy access to a huge customer base is known as B2B manufacturers or suppliers. These manufacturers are generally registered on different web portals to avail maximum profits and business orders. Companies also get one by registering a B2B portal before your competitors do what they would be better known than others in the international market. For example, a supplier of leather shoes can record and display their products in a B2B portal and get orders from abroad.

Today more and more business houses are starting businesses through these B2B trade portals, as it not only gives a larger consumer base, but also increases the efficiency and revenue in no time. However, it means that these providers start their activities only through these portals. By registering a B2B portal however, get access to a global customer base and have an opportunity to improve their business results on a large basis.